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   CLICK ON A NAME BELOW
  1. 2009: Zugasti
  2. 2002: Asero
  3. 2001: Arshad
  4. 1996: Bhatia
  5. 1996: Jimenez-Aranda 
  6. 1995: Lucarelli
  7. 1995: Schapowal
  8. 1994: Nsouli
  9. 1984: Allen
  10. 1983: Wilson
  11. 1978: Neuman



Diet & Allergy
Some of the Research

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Last update 2/18/2014



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  • Allen DH, Van Nunen S, Loblay R, Clarke L, Swain A, Adverse reactions to foods. Med J Aust 1984 Sep 1;141(5 Suppl):S37-42
    "... This, [discovery of IgE in the 1960's] ... has resulted in considerable confusion in the minds of both the public and the medical profession on the subject. In the majority of patients presenting with food intolerance, recognized or otherwise, symptoms are precipitated by various small, non-immunogenic organic molecules present in the food as natural or added ingredients. These reactions are pharmacological rather than immunological in nature, although in some situations ... resulting in similar symptoms."

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  • Arshad SH, Food allergen avoidance in primary prevention of food allergy, Allergy. 2001;56 Suppl 67:113-6.
    " Approximately 5-10% of children suffer from allergy to one or more foods. ... Breastfeeding has many advantages and should be recommended for all children. Those with a history of atopy in the immediate family are at a higher risk and maternal diet during lactation, avoiding highly allergenic foods, may enhance the benefit. Cow's milk should be strictly avoided, and supplements, if required, should be with a hypoallergenic formula. Delayed introduction of egg, nuts, wheat and fish has also been suggested. ... In high risk infants, a combined approach, where breastfeeding with maternal avoidance of highly allergenic foods, supplemented by extensively hydrolysed formula during the first 6 months of life, in addition to the delayed introduction of solid foods, has been shown to reduce the development of food allergy in infants. "

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  • Asero, R. Multiple intolerance to food additives, Letter to the editor of the Journal of Allergy and Clinical Immunology, Volume 110, Issue 3 , Pages 531-532, September 2002
    Case study of a 44-year-old woman given double-blind challenge testing with sulfite, benzoate, MSG, nitrate, tartrazine (Yellow 5), erythrosine (Red 3), sorbic acid, BHA, and talc, although skin prick tests with the usual allergens were negative.

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  • Bhatia MS, Allergy to tartrazine in alprazolam. Indian J Med Sci 1996 Aug;50(8):285-6
    "Allergy to tartrazine-containing psychotropic medication (especially antidepressants) had been reported. 20 patients of apparent allergy to tartrazine-containing alprazolam brands in 480 patients exposed to the dye are described. Rechallenge with non tartrazine-containing alprazolam brands did not produce the similar allergic reactions."

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  • Jimenez-Aranda GS, Flores-Sandoval G, Gomez-Vera J, Orea-Solano M, Prevalence of chronic urticaria following the ingestion of food additives in a third tier hospital Rev Alerg Mex 1996 Nov-Dec;43(6):152-6
    " We studied 40 patients with the clinical diagnostic of chronic urticaria from January to June, 1995 ... We performed a basic clinics history and the oral challenge tests (PRO) included Tartrazine (Ta), Sodium Metabisulfite (MS), Potasium Metabisulfite (MP) and Sodium Bisulfite (BS) in consecutive days with increasing doses unless an adverse reactions appear. ... 63.8% (23/36) had positive PRO. 47.2% (17/36) positives to Ta,, 36.1% (13/36) to MS, 33.3% (12/36) to BS and 30.5% (11/36) to MP. 72.2% (26/36) had positive PC [skin prick test] to one or more foods, 65.3% (17/26) besides had positive PRO. 41.1% (7/17) of the patients who had positive PRO and positive PC to foods had sinusitis. .... Ta was the additive that cause more reactivity. It is possible to find reactivity to one or more additives in a patient with chronic urticaria."

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  • Lucarelli S, et al., Food allergy and infantile autism. Panminerva Med 1995 Sep;37(3):137-41
    "...We noticed a marked improvement in the behavioural symptoms of patients after a period of 8 weeks on an elimination diet ... Our results lead us to hypothesise a relationship between food allergy and infantile autism as has already been suggested for other disturbances of the central nervous system."

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  • Neuman I, Elian R, Nahum H, Shaked P, Creter D., The danger of "yellow dyes" (tartrazine) to allergic subjects. Clin Allergy. 1978 Jan;8(1):65-8.
    " Oral administration of 50 mg tartrazine to 122 patients with a variety of allergic disorders caused the following reactions: general weakness, heatwaves, palpitations, blurred vision, rhinorrhoea, feeling of suffocation, pruritus and urticaria. There was activation of the fibrinolytic pathway . . ."

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  • Nsouli TM, Nsouli SM, Linde RE, O'Mara F, Scanlon RT, Bellanti JA., Role of Food Allergy in Serous Otitis Media., Annals of Allergy 1994 Sep;73(3):215-9
    There was a significant association between food allergy and repeated earaches (recurrent serous otitis media) in 81/104 patients (78%). "The elimination diet led to a significant amelioration of serous otitis media in 70/81 (86%) patients as assessed by clinical evaluation and tympanometry. The challenge diet with the suspected offending food(s) provoked a recurrence of serous otitis media in 66/70 patients (94%). CONCLUSIONS. The possibility of food allergy should be considered in all pediatric patients with recurrent serous otitis media and a diligent search for the putative food allergen made for proper diagnostic and therapeutic intervention."

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  • Schapowal AG, Simon HU, Schmitz-Schumann M, Phenomenology, pathogenesis, diagnosis and treatment of aspirin-sensitive rhinosinusitis. Acta Otorhinolaryngol Belg 1995;49(3):235-50
    "Aspirin-sensitive rhinosinusitis is a non-allergic, non-infectious perennial eosinophilic rhinitis starting in middle age and rarely seen in children. ... There is an intolerance to aspirin and most other NSAID. An intolerance to tartrazine, food additives, alcohol, narcotics and local anaesthetics can follow. Most aspirin-sensitive patients develop nasal polyps. Untreated, it can lead to asthma. The frequency of aspirin intolerance is 6.18% in patients with perennial rhinitis and 14.68% in patients with nasal polyps. ... "

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  • Wilson WH, Recurrent acute otitis media in infants--role of immune complexes acquired in utero. Laryngoscope 1983 Apr;93(4):418-21
    "Ten infants experiencing recurring episodes of acute otitis media with associated otitis media with effusion while on human breast milk afford a study of the role of possible immune complexes acquired in utero through the mother's allergic diathesis. ... Challenge feeding tests determined the mothers' hypersensitivities. Those infants breast fed by mothers exhibiting positive challenges to specific foods, manifest allergic responses themselves following the first breast feeding after the mothers' challenge. A cessation of episodes ... occurred in five ... as foods proven to be offenders were eliminated from the mother's and child's diet..."

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  • Zugasti Murillo A., Food Intolerance. Endocrinologia y Nutricion. 2009 May;56(5):241-50. Epub 2009 Jul 1.
    " Adverse food reactions are common in the general population. Nevertheless, our knowledge of the structure of food allergens and of the mechanisms involved is poor. In 1995 the European Academy of Allergology and Clinical Immunology suggested a classification based on the causative pathogenic mechanism. According to this classification, non-toxic reactions can be divided into food allergies when they recognize immunological mechanisms and food intolerance when there are no immunological implications. The treatment of food intolerance is avoidance of the particular food. There are specific treatments for some food intolerance (beta-galactosidases for the management of lactose intolerance)."

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